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Gene: P2rx3 (purinergic receptor P2X, ligand-gated ion channel, 3) Mus musculus
Symbol: P2rx3
Name: purinergic receptor P2X, ligand-gated ion channel, 3
Description: Exhibits extracellularly ATP-gated cation channel activity. Involved in several processes, including neuromuscular synaptic transmission; response to ATP; and smooth muscle contraction. Localizes to the Schaffer collateral - CA1 synapse; axon; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including branchial arch; embryo ectoderm; nervous system; retina; and skin. Orthologous to human P2RX3 (purinergic receptor P2X 3); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930513E20Rik; ATP receptor; hypothetical protein LOC78804; MGC28163; P2X purinoceptor 3; P2X3; purinergic receptor P2X3; RIKEN cDNA 4930513E20 gene
Homo sapiens (human) : P2RX3 (purinergic receptor P2X 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P2rx3 (purinergic receptor P2X 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx3 (purinergic receptor P2X 3)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX3 (purinergic receptor P2X 3)
Canis lupus familiaris (dog) : P2RX3 (purinergic receptor P2X 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx3 (purinergic receptor P2X 3)
Sus scrofa (pig) : P2RX3 (purinergic receptor P2X 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl284,998,583 - 85,037,462 (-)Ensembl
GRCm38284,996,549 - 85,037,108 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37284,836,709 - 84,875,991 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,797,391 - 84,836,673 (-)NCBImm8
Celera286,595,241 - 86,634,592 (-)NCBICelera
Cytogenetic Map2 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on P2rx3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735322
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.