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Gene: HTR5A (5-hydroxytryptamine receptor 5A) Homo sapiens
Symbol: HTR5A
Name: 5-hydroxytryptamine receptor 5A
Description: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-HT-5; 5-HT-5A; 5-HT5A; 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled; MGC138226; serotonin receptor 5A
Mus musculus (house mouse) : Htr5a (5-hydroxytryptamine (serotonin) receptor 5A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Htr5a (5-hydroxytryptamine receptor 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr5a (5-hydroxytryptamine receptor 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR5A (5-hydroxytryptamine receptor 5A)
Canis lupus familiaris (dog) : HTR5A (5-hydroxytryptamine receptor 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr5a (5-hydroxytryptamine receptor 5A)
Sus scrofa (pig) : HTR5A (5-hydroxytryptamine receptor 5A)
more info ...
Related Pseudogenes: HTR5BP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387155,070,324 - 155,087,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377154,862,034 - 154,879,102 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,493,479 - 154,508,392 (+)NCBINCBI36hg18NCBI36
Build 347154,300,257 - 154,313,845NCBI
Celera7149,280,016 - 149,294,949 (+)NCBI
Cytogenetic Map7q36.2NCBI
HuRef7148,594,438 - 148,611,518 (+)NCBIHuRef
CHM1_17154,870,423 - 154,887,497 (+)NCBICHM1_1
CRA_TCAGchr7v27154,090,358 - 154,107,446 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HTR5A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735325
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.