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Gene: ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1) Homo sapiens
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Symbol: ATP1A1
Name: ATPase Na+/K+ transporting subunit alpha 1
CRRD ID: 735332
Description: Exhibits chaperone binding activity; sodium:potassium-exchanging ATPase activity; and steroid hormone binding activity. Involved in several processes, including cellular monovalent inorganic cation homeostasis; cellular response to steroid hormone stimulus; and ion transmembrane transport. Localizes to several cellular components, including T-tubule; lateral plasma membrane; and sodium:potassium-exchanging ATPase complex. Implicated in Charcot-Marie-Tooth disease type 2DD.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Na+/K+ transporting, alpha 1 polypeptide; CMT2DD; HOMGSMR2; MGC3285; MGC51750; Na(+)/K(+) ATPase alpha-1 subunit; Na+, K+ ATPase alpha subunit; Na+/K+ ATPase 1; Na, K-ATPase, alpha-A catalytic polypeptide; Na,K-ATPase alpha-1 subunit; Na,K-ATPase catalytic subunit alpha-A protein; sodium pump 1; sodium pump subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-1; sodium-potassium-ATPase, alpha 1 polypeptide; sodium/potassium-transporting ATPase subunit alpha-1
Orthologs:
Mus musculus (house mouse) : Atp1a1 (ATPase, Na+/K+ transporting, alpha 1 polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Canis lupus familiaris (dog) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)
Sus scrofa (pig) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Chlorocebus sabaeus (African green monkey) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Heterocephalus glaber (naked mole-rat) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   BP45_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1116,372,668 - 116,410,261 (+)EnsemblGRCh38hg38GRCh38
GRCh381116,372,986 - 116,410,259 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371116,914,802 - 116,948,069 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361116,717,359 - 116,748,919 (+)NCBINCBI36hg18NCBI36
Build 341116,627,877 - 116,659,436NCBI
Celera1115,144,421 - 115,176,022 (+)NCBI
Cytogenetic Map1p13.1NCBI
HuRef1114,773,961 - 114,805,562 (+)NCBIHuRef
CHM1_11117,030,620 - 117,062,221 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ATP1A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735332
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.