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Analyze GeneStrainQTL List |
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GOLF (Gene-Ortholog Location Finder) |
![]() Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | RGD:2658 | 6480464 | [Estradiol co-treated with Plant Preparations] results in increased expression of GALR3 mRNA | CTD | PMID:26945725 | 17beta-estradiol | increases expression | ISO | RGD:2658 | 6480464 | Estradiol results in increased expression of GALR3 mRNA | CTD | PMID:26945725 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of GALR3 mRNA | CTD | PMID:22100608 | ammonium chloride | affects expression | ISO | RGD:2658 | 6480464 | Ammonium Chloride affects the expression of GALR3 mRNA | CTD | PMID:16483693 | bisphenol A | decreases expression | ISO | RGD:2658 | 6480464 | bisphenol A results in decreased expression of GALR3 mRNA | CTD | PMID:25181051 | clofibrate | decreases expression | ISO | RGD:735334 | 6480464 | Clofibrate results in decreased expression of GALR3 mRNA | CTD | PMID:17585979 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of GALR3 mRNA | CTD | PMID:18175754 | lead(0) | decreases expression | EXP | | 6480464 | Lead results in decreased expression of GALR3 mRNA | CTD | PMID:19921347 | lead(2+) | decreases expression | EXP | | 6480464 | Lead results in decreased expression of GALR3 mRNA | CTD | PMID:19921347 | methylmercury chloride | decreases expression | ISO | RGD:735334 | 6480464 | methylmercuric chloride results in decreased expression of GALR3 mRNA | CTD | PMID:21385734 | paracetamol | affects expression | ISO | RGD:735334 | 6480464 | Acetaminophen affects the expression of GALR3 mRNA | CTD | PMID:17562736 | quercitrin | increases expression | EXP | | 6480464 | quercitrin results in increased expression of GALR3 mRNA | CTD | PMID:25193878 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of GALR3 gene | CTD | PMID:29154799 | vitamin E | increases expression | EXP | | 6480464 | Vitamin E results in increased expression of GALR3 mRNA | CTD | PMID:19244175 | |
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1. | GOA_HUMAN data from the GO Consortium |
2. | RGD automated import pipeline for gene-chemical interactions |
3. | Smith KE, etal., J Biol Chem 1998 Sep 4;273(36):23321-6. |
PubMed | 2834384 9832121 9928159 10441207 10591208 11867941 17083333 18577758 19086053 20398908 20677014 20817064 20848231 21873635 22889491 24517231 24706871 27940914 28154160 28844939 |
GALR3 (Homo sapiens - human) |
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Galr3 (Mus musculus - house mouse) |
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Galr3 (Rattus norvegicus - Norway rat) |
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Galr3 (Chinchilla lanigera - long-tailed chinchilla) |
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GALR3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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GALR3 (Canis lupus familiaris - dog) |
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Galr3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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GALR3 (Sus scrofa - pig) |
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GALR3 |
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The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
RefSeq Transcripts | NM_003614 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
GenBank Nucleotide | AB065934 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AF067733 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AF073799 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AH008056 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AX646279 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AY587582 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH471095 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
Z97630 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_003614 ⟹ NP_003605 | ||||||||||||||||||||||||||||||||||
RefSeq Status: | REVIEWED | ||||||||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||||||||
Position: |
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Sequence: |
TCCCAGGTGCCCGTCTGATGGGGAGATGGCTGATGCCCAGAACATTTCACTGGACAGCCCAGGGhide sequence |
Protein RefSeqs | NP_003605 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAC18860 | (Get FASTA) | NCBI Sequence Viewer |
AAC35944 | (Get FASTA) | NCBI Sequence Viewer | |
AAD47348 | (Get FASTA) | NCBI Sequence Viewer | |
AAS98215 | (Get FASTA) | NCBI Sequence Viewer | |
BAC06149 | (Get FASTA) | NCBI Sequence Viewer | |
CAD69270 | (Get FASTA) | NCBI Sequence Viewer | |
EAW60191 | (Get FASTA) | NCBI Sequence Viewer | |
O60755 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_003605 ⟸ NM_003614 |
- UniProtKB: | O60755 (UniProtKB/Swiss-Prot) |
- Sequence: |
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLhide sequence |
Name | Type | Condition(s) | Position(s) | Clinical significance |
GRCh38/hg38 22q12.3-13.1(chr22:35333993-38900177)x1 | copy number loss | Polydactyly [RCV000051364]|See cases [RCV000051364] | Chr22:35333993..38900177 [GRCh38] Chr22:35729986..39296182 [GRCh37] Chr22:34059986..37626128 [NCBI36] Chr22:22q12.3-13.1 |
pathogenic |
GRCh38/hg38 22q12.3-13.1(chr22:36859030-39236985)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051366]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051366]|See cases [RCV000051366] | Chr22:36859030..39236985 [GRCh38] Chr22:37255072..39632990 [GRCh37] Chr22:35585018..37962936 [NCBI36] Chr22:22q12.3-13.1 |
pathogenic |
GRCh38/hg38 22q13.1(chr22:37721777-38886664)x1 | copy number loss | Hearing impairment [RCV000051367]|See cases [RCV000051367] | Chr22:37721777..38886664 [GRCh38] Chr22:38117784..39282669 [GRCh37] Chr22:36447730..37612615 [NCBI36] Chr22:22q13.1 |
pathogenic |
GRCh38/hg38 22q12.3-13.1(chr22:36068124-38002382)x3 | copy number gain | Hearing impairment [RCV000051683]|See cases [RCV000051683] | Chr22:36068124..38002382 [GRCh38] Chr22:36464172..38398389 [GRCh37] Chr22:34794118..36728335 [NCBI36] Chr22:22q12.3-13.1 |
pathogenic |
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 | copy number gain | Global developmental delay [RCV000051684]|See cases [RCV000051684] | Chr22:37061769..50738932 [GRCh38] Chr22:37457809..51177360 [GRCh37] Chr22:35787755..49524226 [NCBI36] Chr22:22q12.3-13.33 |
pathogenic |
GRCh38/hg38 22q13.1-13.2(chr22:37721797-40860953)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051685]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051685]|See cases [RCV000051685] | Chr22:37721797..40860953 [GRCh38] Chr22:38117804..41256957 [GRCh37] Chr22:36447750..39586903 [NCBI36] Chr22:22q13.1-13.2 |
pathogenic |
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 | copy number gain | Failure to thrive [RCV000051682]|See cases [RCV000051682] | Chr22:33768441..50739977 [GRCh38] Chr22:34164428..51178405 [GRCh37] Chr22:32494428..49525271 [NCBI36] Chr22:22q12.3-13.33 |
pathogenic |
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 | copy number gain | See cases [RCV000133646] | Chr22:16916608..50739836 [GRCh38] Chr22:17397498..51178264 [GRCh37] Chr22:15777498..49525130 [NCBI36] Chr22:22q11.1-13.33 |
pathogenic |
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 | copy number gain | See cases [RCV000134730] | Chr22:16916743..50739785 [GRCh38] Chr22:17397633..51178213 [GRCh37] Chr22:15777633..49525079 [NCBI36] Chr22:22q11.1-13.33 |
pathogenic |
GRCh38/hg38 22q13.1(chr22:37447222-39103680)x1 | copy number loss | See cases [RCV000141783] | Chr22:37447222..39103680 [GRCh38] Chr22:37843259..39499685 [GRCh37] Chr22:36173205..37829631 [NCBI36] Chr22:22q13.1 |
pathogenic |
GRCh37/hg19 22q12.3-13.1(chr22:37090025-39601950)x3 | copy number gain | See cases [RCV000446037] | Chr22:37090025..39601950 [GRCh37] Chr22:22q12.3-13.1 |
uncertain significance |
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237518)x3 | copy number gain | See cases [RCV000240091] | Chr22:16054691..51237518 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q12.3-13.33(chr22:35728929-51220961)x3 | copy number gain | See cases [RCV000240469] | Chr22:35728929..51220961 [GRCh37] Chr22:22q12.3-13.33 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51220902)x3 | copy number gain | See cases [RCV000446956] | Chr22:16054691..51220902 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237463)x3 | copy number gain | See cases [RCV000448847] | Chr22:16054691..51237463 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q13.1(chr22:37866631-39054815)x1 | copy number loss | See cases [RCV000511673] | Chr22:37866631..39054815 [GRCh37] Chr22:22q13.1 |
pathogenic |
GRCh37/hg19 22q12.3-13.1(chr22:36877226-38548989)x1 | copy number loss | See cases [RCV000512008] | Chr22:36877226..38548989 [GRCh37] Chr22:22q12.3-13.1 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838) | copy number gain | See cases [RCV000510873] | Chr22:16888900..51197838 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838)x3 | copy number gain | See cases [RCV000512333] | Chr22:16888900..51197838 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q12.3-13.1(chr22:35674826-39466442)x3 | copy number gain | See cases [RCV000512385] | Chr22:35674826..39466442 [GRCh37] Chr22:22q12.3-13.1 |
likely pathogenic |
GRCh38/hg38 22q13.1(chr22:37805546-37983784)x1 | copy number loss | Waardenburg syndrome type 4C [RCV000721944] | Chr22:37805546..37983784 [GRCh38] Chr22:38201553..38379791 [GRCh37] Chr22:22q13.1 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16054667-51243435)x3 | copy number gain | not provided [RCV000741689] | Chr22:16054667..51243435 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51195728)x3 | copy number gain | not provided [RCV000741691] | Chr22:16114244..51195728 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q13.1(chr22:38212254-38222112)x3 | copy number gain | not provided [RCV000741961] | Chr22:38212254..38222112 [GRCh37] Chr22:22q13.1 |
benign |
GRCh37/hg19 22q13.1(chr22:38213383-38222112)x3 | copy number gain | not provided [RCV000741962] | Chr22:38213383..38222112 [GRCh37] Chr22:22q13.1 |
benign |
GRCh37/hg19 22q13.1(chr22:38216758-38222112)x3 | copy number gain | not provided [RCV000741963] | Chr22:38216758..38222112 [GRCh37] Chr22:22q13.1 |
benign |
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51211392)x3 | copy number gain | not provided [RCV000741692] | Chr22:16114244..51211392 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
GRCh37/hg19 22q11.1-13.33(chr22:16888899-51197838)x3 | copy number gain | not provided [RCV000846344] | Chr22:16888899..51197838 [GRCh37] Chr22:22q11.1-13.33 |
pathogenic |
Database | Acc Id | Source(s) |
AGR Gene | HGNC:4134 | AgrOrtholog |
COSMIC | GALR3 | COSMIC |
Ensembl Genes | ENSG00000128310 | ENTREZGENE, UniProtKB/Swiss-Prot |
Ensembl Protein | ENSP00000249041 | ENTREZGENE, UniProtKB/Swiss-Prot |
Ensembl Transcript | ENST00000249041 | ENTREZGENE, UniProtKB/Swiss-Prot |
GTEx | ENSG00000128310 | GTEx |
HGNC ID | HGNC:4134 | ENTREZGENE |
Human Proteome Map | GALR3 | Human Proteome Map |
InterPro | Galanin_rcpt | UniProtKB/Swiss-Prot |
Galnin_3_rcpt | UniProtKB/Swiss-Prot | |
GPCR_Rhodpsn | UniProtKB/Swiss-Prot | |
GPCR_Rhodpsn_7TM | UniProtKB/Swiss-Prot | |
KEGG Report | hsa:8484 | UniProtKB/Swiss-Prot |
NCBI Gene | 8484 | ENTREZGENE |
OMIM | 603692 | OMIM |
Pfam | 7tm_1 | UniProtKB/Swiss-Prot |
PharmGKB | PA28547 | PharmGKB |
PRINTS | GALANIN3R | UniProtKB/Swiss-Prot |
GALANINR | UniProtKB/Swiss-Prot | |
GPCRRHODOPSN | UniProtKB/Swiss-Prot | |
PROSITE | G_PROTEIN_RECEP_F1_1 | UniProtKB/Swiss-Prot |
G_PROTEIN_RECEP_F1_2 | UniProtKB/Swiss-Prot | |
UniGene | Hs.158353 | ENTREZGENE |
UniProt | GALR3_HUMAN | UniProtKB/Swiss-Prot, ENTREZGENE |
UniProt Secondary | Q53YJ4 | UniProtKB/Swiss-Prot |
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More on GALR3 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: hg19 hg38 |
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HGNC Report |
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NCBI Genome Data Viewer |
CRRD Object Information | |
CRRD ID: | 735333 |
Created: | 2004-02-06 |
Species: | Homo sapiens |
Last Modified: | 2019-11-26 |
Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.