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Gene: DMBT1 (deleted in malignant brain tumors 1) Homo sapiens
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Symbol: DMBT1
Name: deleted in malignant brain tumors 1
CRRD ID: 735357
Description: Exhibits several functions, including heparan sulfate binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to bacterium; and receptor-mediated endocytosis. Localizes to extracellular space and phagocytic vesicle membrane. Implicated in glioblastoma multiforme.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deleted in malignant brain tumors 1 protein; FLJ61058; glycoprotein 340; gp-340; GP340; hensin; MGC164738; muclin; SAG; salivary agglutinin; salivary scavenger and agglutinin; SALSA; surfactant pulmonary-associated D-binding protein; vomeroglandin
Orthologs:
Mus musculus (house mouse) : Dmbt1 (deleted in malignant brain tumors 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dmbt1 (deleted in malignant brain tumors 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dmbt1 (deleted in malignant brain tumors 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DMBT1 (deleted in malignant brain tumors 1)
Canis lupus familiaris (dog) : DMBT1 (deleted in malignant brain tumors 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dmbt1 (deleted in malignant brain tumors 1)
Sus scrofa (pig) : DMBT1 (deleted in malignant brain tumors 1)
Chlorocebus sabaeus (African green monkey) : DMBT1 (deleted in malignant brain tumors 1)
Heterocephalus glaber (naked mole-rat) : Dmbt1 (deleted in malignant brain tumors 1)
more info ...
Related Pseudogenes: DMBT1L1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10122,560,665 - 122,643,740 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl10122,560,665 - 122,643,736 (+)EnsemblGRCh38hg38GRCh38
GRCh3810122,560,677 - 122,643,736 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710124,320,181 - 124,403,252 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610124,310,171 - 124,393,242 (+)NCBINCBI36hg18NCBI36
Build 3410124,310,170 - 124,393,242NCBI
Celera10118,052,442 - 118,110,650 (+)NCBI
Cytogenetic Map10q26.13NCBI
HuRef10117,951,140 - 118,021,117 (+)NCBIHuRef
CHM1_110124,604,802 - 124,685,026 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on DMBT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735357
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.