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Gene: ZP2 (zona pellucida glycoprotein 2) Homo sapiens
Symbol: ZP2
Name: zona pellucida glycoprotein 2
Description: Exhibits acrosin binding activity and identical protein binding activity. Predicted to be involved in binding activity of sperm to zona pellucida and prevention of polyspermy. Localizes to the egg coat.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OOMD6; zona pellucida glycoprotein 2 (sperm receptor); zona pellucida glycoprotein ZP2; zona pellucida protein A; zona pellucida sperm-binding protein 2; Zp-2; ZPA
Mus musculus (house mouse) : Zp2 (zona pellucida glycoprotein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zp2 (zona pellucida glycoprotein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zp2 (zona pellucida glycoprotein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZP2 (zona pellucida glycoprotein 2)
Canis lupus familiaris (dog) : ZP2 (zona pellucida glycoprotein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zp2 (zona pellucida glycoprotein 2)
Sus scrofa (pig) : ZP2 (zona pellucida glycoprotein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381621,197,450 - 21,214,510 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371621,208,773 - 21,225,831 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,116,274 - 21,130,369 (-)NCBINCBI36hg18NCBI36
Build 341621,116,273 - 21,130,369NCBI
Celera1620,518,619 - 20,532,706 (-)NCBI
Cytogenetic Map16p12.3-p12.2NCBI
HuRef1619,743,981 - 19,758,073 (-)NCBIHuRef
CHM1_11621,296,024 - 21,313,083 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735363
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.