Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: XPO1 (exportin 1) Homo sapiens
Symbol: XPO1
Name: exportin 1
Description: Exhibits nuclear export signal receptor activity. Involved in ribosomal large subunit export from nucleus and ribosomal small subunit export from nucleus. Localizes to several cellular components, including the annulate lamellae; kinetochore; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chromosome region maintenance 1 homolog; chromosome region maintenance 1 protein homolog; CRM-1; CRM1; CRM1, yeast, homolog; DKFZp686B1823; emb; exp1; exportin 1 (CRM1 homolog, yeast); exportin 1 (CRM1, yeast, homolog); exportin-1; Exportin-1 (required for chromosome region maintenance)
Mus musculus (house mouse) : Xpo1 (exportin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xpo1 (exportin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpo1 (exportin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XPO1 (exportin 1)
Canis lupus familiaris (dog) : XPO1 (exportin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpo1 (exportin 1)
Sus scrofa (pig) : XPO1 (exportin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38261,477,849 - 61,538,522 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37261,705,069 - 61,765,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,558,573 - 61,618,922 (-)NCBINCBI36hg18NCBI36
Build 34261,616,719 - 61,677,069NCBI
Celera261,550,297 - 61,610,634 (-)NCBI
Cytogenetic Map2p15NCBI
HuRef261,445,666 - 61,506,245 (-)NCBIHuRef
CHM1_1261,635,341 - 61,695,639 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XPO1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735365
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.