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Gene: XPO1 (exportin 1) Homo sapiens
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Symbol: XPO1
Name: exportin 1
Description: Exhibits nuclear export signal receptor activity. Involved in ribosomal large subunit export from nucleus and ribosomal small subunit export from nucleus. Localizes to several cellular components, including the annulate lamellae; kinetochore; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chromosome region maintenance 1 homolog; chromosome region maintenance 1 protein homolog; CRM-1; CRM1; CRM1, yeast, homolog; DKFZp686B1823; emb; exp1; exportin 1 (CRM1 homolog, yeast); exportin 1 (CRM1, yeast, homolog); exportin-1; Exportin-1 (required for chromosome region maintenance)
Orthologs:
Mus musculus (house mouse) : Xpo1 (exportin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xpo1 (exportin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpo1 (exportin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XPO1 (exportin 1)
Canis lupus familiaris (dog) : XPO1 (exportin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpo1 (exportin 1)
Sus scrofa (pig) : XPO1 (exportin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38261,477,849 - 61,538,522 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37261,705,069 - 61,765,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,558,573 - 61,618,922 (-)NCBINCBI36hg18NCBI36
Build 34261,616,719 - 61,677,069NCBI
Celera261,550,297 - 61,610,634 (-)NCBI
Cytogenetic Map2p15NCBI
HuRef261,445,666 - 61,506,245 (-)NCBIHuRef
CHM1_1261,635,341 - 61,695,639 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XPO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735365
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.