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Gene: PDE6G (phosphodiesterase 6G) Homo sapiens
Symbol: PDE6G
Name: phosphodiesterase 6G
Description: Predicted to have enzyme inhibitor activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to the photoreceptor outer segment membrane. Implicated in retinitis pigmentosa 57.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686C0587; GMP-PDE gamma; MGC125749; PDEG; phosphodiesterase 6G, cGMP-specific, rod, gamma; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57
Mus musculus (house mouse) : Pde6g (phosphodiesterase 6G, cGMP-specific, rod, gamma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde6g (phosphodiesterase 6G)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde6g (phosphodiesterase 6G)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE6G (phosphodiesterase 6G)
Canis lupus familiaris (dog) : PDE6G (phosphodiesterase 6G)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde6g (phosphodiesterase 6G)
Sus scrofa (pig) : PDE6G (phosphodiesterase 6G)
Chlorocebus sabaeus (green monkey) : PDE6G (phosphodiesterase 6G)
Heterocephalus glaber (naked mole-rat) : Pde6g (phosphodiesterase 6G)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1781,650,459 - 81,663,112 (-)Ensembl
GRCh381781,650,459 - 81,663,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,617,489 - 79,623,607 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,227,894 - 77,234,038 (-)NCBINCBI36hg18NCBI36
Build 341777,227,654 - 77,233,971NCBI
Celera1776,262,515 - 76,268,615 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1775,063,689 - 75,069,807 (-)NCBIHuRef
CHM1_11779,703,710 - 79,709,828 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PDE6G
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735391
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.