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Gene: Cfl1 (cofilin 1, non-muscle) Mus musculus
Symbol: Cfl1
Name: cofilin 1, non-muscle
CRRD ID: 735417
Description: Exhibits actin filament binding activity and signaling receptor binding activity. Involved in several processes, including actin filament fragmentation; neural fold formation; and positive regulation of actin filament depolymerization. Localizes to cell-cell junction; cortical actin cytoskeleton; and lamellipodium. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and immune system. Orthologous to human CFL1 (cofilin 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA959946; co; Cof; cofilin, non-muscle isoform; cofilin-1; n-c; n-cofilin
Homo sapiens (human) : CFL1 (cofilin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cfl1 (cofilin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfl1 (cofilin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CFL1 (cofilin 1)
Canis lupus familiaris (dog) : CFL1 (cofilin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfl1 (cofilin 1)
Sus scrofa (pig) : CFL1 (cofilin 1)
Chlorocebus sabaeus (African green monkey) : CFL1 (cofilin 1)
Heterocephalus glaber (naked mole-rat) : Cfl1 (cofilin 1)
more info ...
Related Pseudogenes: Gm12310   Gm14108   Gm14933   Gm15660   Gm18121   Gm18131   Gm18133   Gm6180   Gm8629   Gm8682   Gm8785  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl195,490,455 - 5,495,201 (+)EnsemblGRCm38mm10GRCm38
GRCm38195,490,455 - 5,494,031 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,490,455 - 5,494,031 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,490,525 - 5,495,201 (+)NCBImm8
Celera195,362,154 - 5,365,730 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cfl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735417
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.