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Gene: Slit2 (slit guidance ligand 2) Mus musculus
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Symbol: Slit2
Name: slit guidance ligand 2
CRRD ID: 735484
Description: Exhibits chemorepellent activity. Involved in several processes, including animal organ development; generation of neurons; and negative chemotaxis. Localizes to extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Kartagener syndrome; cystic kidney disease; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human SLIT2 (slit guidance ligand 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: b2b1200.1Clo; downregulated during adipocyte differentiation-1; Drad; Drad-1; E030015M03Rik; E130320P19Rik; KIAA4141; mKIAA4141; neurogenic extracellular slit protein; S; Slil3; slit homolog 2 (Drosophila); slit homolog 2 protein; slit-2
Orthologs:
Homo sapiens (human) : SLIT2 (slit guidance ligand 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slit2 (slit guidance ligand 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slit2 (slit guidance ligand 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLIT2 (slit guidance ligand 2)
Canis lupus familiaris (dog) : SLIT2 (slit guidance ligand 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slit2 (slit guidance ligand 2)
Sus scrofa (pig) : SLIT2 (slit guidance ligand 2)
Chlorocebus sabaeus (African green monkey) : SLIT2 (slit guidance ligand 2)
Heterocephalus glaber (naked mole-rat) : Slit2 (slit guidance ligand 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39548,138,633 - 48,465,077 (+)NCBI
GRCm38547,981,291 - 48,307,735 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl547,983,138 - 48,307,733 (+)EnsemblGRCm38mm10GRCm38
MGSCv37548,374,394 - 48,697,017 (+)NCBIGRCm37mm9NCBIm37
MGSCv36548,273,041 - 48,593,759 (+)NCBImm8
Celera545,381,658 - 45,708,133 (+)NCBICelera
Cytogenetic Map5B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Slit2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735484
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.