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Gene: SCN4B (sodium voltage-gated channel beta subunit 4) Homo sapiens
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Symbol: SCN4B
Name: sodium voltage-gated channel beta subunit 4
Description: Exhibits ion channel binding activity; sodium channel regulator activity; and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Involved in several processes, including cardiac muscle cell action potential; regulation of heart rate by cardiac conduction; and regulation of ion transport. Localizes to the voltage-gated sodium channel complex. Implicated in long QT syndrome 10.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB17; LQT10; Navbeta4; sodium channel beta-4 subunit; sodium channel subunit beta-4; sodium channel, voltage gated, type IV beta subunit; sodium channel, voltage-gated, type IV, beta subunit
Orthologs:
Mus musculus (house mouse) : Scn4b (sodium channel, type IV, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scn4b (sodium voltage-gated channel beta subunit 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn4b (sodium voltage-gated channel beta subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN4B (sodium voltage-gated channel beta subunit 4)
Canis lupus familiaris (dog) : SCN4B (sodium voltage-gated channel beta subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn4b (sodium voltage-gated channel beta subunit 4)
Sus scrofa (pig) : SCN4B (sodium voltage-gated channel beta subunit 4)
Chlorocebus sabaeus (African green monkey) : SCN4B (sodium voltage-gated channel beta subunit 4)
Heterocephalus glaber (naked mole-rat) : Scn4b (sodium voltage-gated channel beta subunit 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11118,133,377 - 118,152,888 (-)EnsemblGRCh38hg38GRCh38
GRCh3811118,133,377 - 118,152,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,004,092 - 118,023,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,509,302 - 117,528,747 (-)NCBINCBI36hg18NCBI36
Build 3411117,509,301 - 117,528,745NCBI
Celera11115,161,938 - 115,181,485 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11113,937,739 - 113,957,294 (-)NCBIHuRef
CHM1_111117,889,900 - 117,909,461 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
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External Database Links
Nomenclature History
 
More on SCN4B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735494
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.