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Gene: Hspb8 (heat shock protein 8) Mus musculus
Symbol: Hspb8
Name: heat shock protein 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to localize to the chaperone complex; cytosol; and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HSPB8 (heat shock protein family B (small) member 8); INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-crystallin C chain; AU018630; AW413033; Cryac; crystallin, alpha C; D5Ucla4; E2IG1; H11; H11K; heat shock 27kDa protein 8; heat shock protein 20-like protein; heat shock protein beta-8; HSP20-like; HSP22; small stress protein-like protein HSP22
Homo sapiens (human) : HSPB8 (heat shock protein family B (small) member 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hspb8 (heat shock protein family B (small) member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspb8 (heat shock protein family B (small) member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPB8 (heat shock protein family B (small) member 8)
Canis lupus familiaris (dog) : HSPB8 (heat shock protein family B (small) member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965479 (uncharacterized LOC101965479)
Sus scrofa (pig) : HSPB8 (heat shock protein family B (small) member 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm385116,408,491 - 116,422,864 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375116,858,504 - 116,872,873 (-)NCBIGRCm37mm9NCBIm37
MGSCv365116,669,494 - 116,683,863 (-)NCBImm8
Celera5113,505,586 - 113,520,087 (-)NCBICelera
Cytogenetic Map5 FNCBI
cM Map556.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hspb8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735524
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.