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Gene: Hspb8 (heat shock protein 8) Mus musculus
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Symbol: Hspb8
Name: heat shock protein 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to localize to the chaperone complex; cytosol; and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HSPB8 (heat shock protein family B (small) member 8); INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-crystallin C chain; AU018630; AW413033; Cryac; crystallin, alpha C; D5Ucla4; E2IG1; H11; H11K; heat shock 27kDa protein 8; heat shock protein 20-like protein; heat shock protein beta-8; HSP20-like; HSP22; small stress protein-like protein HSP22
Orthologs:
Homo sapiens (human) : HSPB8 (heat shock protein family B (small) member 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hspb8 (heat shock protein family B (small) member 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspb8 (heat shock protein family B (small) member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPB8 (heat shock protein family B (small) member 8)
Canis lupus familiaris (dog) : HSPB8 (heat shock protein family B (small) member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965479 (uncharacterized LOC101965479)
Sus scrofa (pig) : HSPB8 (heat shock protein family B (small) member 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm385116,408,491 - 116,422,864 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375116,858,504 - 116,872,873 (-)NCBIGRCm37mm9NCBIm37
MGSCv365116,669,494 - 116,683,863 (-)NCBImm8
Celera5113,505,586 - 113,520,087 (-)NCBICelera
Cytogenetic Map5 FNCBI
cM Map556.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hspb8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735524
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.