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Gene: FBP1 (fructose-bisphosphatase 1) Homo sapiens
Symbol: FBP1
Name: fructose-bisphosphatase 1
Description: Exhibits several functions, including RNA polymerase II transcription factor binding activity; cation binding activity; and fructose 1,6-bisphosphate 1-phosphatase activity. Involved in several processes, including cellular response to magnesium ion; gluconeogenesis; and regulation of cellular carbohydrate metabolic process. Localizes to the cytoplasm and nucleus. Implicated in fructose-1,6-bisphosphatase deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBP; FBPase 1; fructose-1,6- biphosphatase 1; fructose-1,6-bisphosphatase 1; growth-inhibiting protein 17; liver FBPase
Mus musculus (house mouse) : Fbp1 (fructose bisphosphatase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbp1 (fructose-bisphosphatase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbp1 (fructose-bisphosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBP1 (fructose-bisphosphatase 1)
Canis lupus familiaris (dog) : FBP1 (fructose-bisphosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbp1 (fructose-bisphosphatase 1)
Sus scrofa (pig) : FBP1 (fructose-bisphosphatase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38994,603,133 - 94,640,258 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37997,365,415 - 97,402,531 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36996,405,236 - 96,441,624 (-)NCBINCBI36hg18NCBI36
Build 34994,444,977 - 94,481,358NCBI
Celera967,806,446 - 67,843,550 (-)NCBI
Cytogenetic Map9q22.32NCBI
HuRef966,974,069 - 67,011,150 (-)NCBIHuRef
CHM1_1997,511,867 - 97,548,958 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FBP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735552
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.