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Gene: FBP1 (fructose-bisphosphatase 1) Homo sapiens
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Symbol: FBP1
Name: fructose-bisphosphatase 1
Description: Exhibits several functions, including RNA polymerase II transcription factor binding activity; cation binding activity; and fructose 1,6-bisphosphate 1-phosphatase activity. Involved in several processes, including cellular response to magnesium ion; gluconeogenesis; and regulation of cellular carbohydrate metabolic process. Localizes to the cytoplasm and nucleus. Implicated in fructose-1,6-bisphosphatase deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBP; FBPase 1; fructose-1,6- biphosphatase 1; fructose-1,6-bisphosphatase 1; growth-inhibiting protein 17; liver FBPase
Orthologs:
Mus musculus (house mouse) : Fbp1 (fructose bisphosphatase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbp1 (fructose-bisphosphatase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbp1 (fructose-bisphosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBP1 (fructose-bisphosphatase 1)
Canis lupus familiaris (dog) : FBP1 (fructose-bisphosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbp1 (fructose-bisphosphatase 1)
Sus scrofa (pig) : FBP1 (fructose-bisphosphatase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38994,603,133 - 94,640,258 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37997,365,415 - 97,402,531 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36996,405,236 - 96,441,624 (-)NCBINCBI36hg18NCBI36
Build 34994,444,977 - 94,481,358NCBI
Celera967,806,446 - 67,843,550 (-)NCBI
Cytogenetic Map9q22.32NCBI
HuRef966,974,069 - 67,011,150 (-)NCBIHuRef
CHM1_1997,511,867 - 97,548,958 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FBP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735552
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.