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Gene: PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3) Homo sapiens
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Symbol: PFKFB3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
CRRD ID: 735560
Description: Predicted to have 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; FLJ37326; fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; iPFK-2; IPFK2; PFK/FBPase 3; PFK2; renal carcinoma antigen NY-REN-56
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl106,144,934 - 6,254,644 (+)EnsemblGRCh38hg38GRCh38
GRCh38106,144,918 - 6,254,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37106,186,843 - 6,277,508 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36106,284,901 - 6,317,501 (+)NCBINCBI36hg18NCBI36
Build 34106,284,900 - 6,317,500NCBI
Celera106,116,166 - 6,206,226 (+)NCBI
Cytogenetic Map10p15.1NCBI
HuRef106,113,180 - 6,203,192 (+)NCBIHuRef
CHM1_1106,186,884 - 6,276,773 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PFKFB3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735560
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.