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Gene: IL10 (interleukin 10) Homo sapiens
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Symbol: IL10
Name: interleukin 10
Description: Exhibits protein dimerization activity. Involved in several processes, including negative regulation of cellular catabolic process; regulation of cytokine secretion; and regulation of macromolecule biosynthetic process. Localizes to the extracellular space. Implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); diabetes mellitus (multiple); eye disease (multiple); and hematologic cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CSIF; cytokine synthesis inhibitory factor; GVHDS; IL-10; IL10A; interleukin-10; MGC126450; MGC126451; T-cell growth inhibitory factor; TGIF
Orthologs:
Mus musculus (house mouse) : Il10 (interleukin 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il10 (interleukin 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il10 (interleukin 10)
Pan paniscus (bonobo/pygmy chimpanzee) : IL10 (interleukin 10)
Canis lupus familiaris (dog) : IL10 (interleukin 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il10 (interleukin 10)
Sus scrofa (pig) : IL10 (interleukin 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,767,602 - 206,772,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371206,940,948 - 206,945,839 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,007,571 - 205,012,462 (-)NCBINCBI36hg18NCBI36
Build 341203,329,342 - 203,334,234NCBI
Celera1180,192,396 - 180,197,294 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1177,639,274 - 177,644,165 (-)NCBIHuRef
CHM1_11208,213,574 - 208,218,465 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated