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Gene: Ivd (isovaleryl coenzyme A dehydrogenase) Mus musculus
Symbol: Ivd
Name: isovaleryl coenzyme A dehydrogenase
Description: Predicted to have isovaleryl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase and leucine catabolic process. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and isovaleric acidemia. Is expressed in several structures, including alimentary system; brain; ear; genitourinary system; and respiratory system. Orthologous to human IVD (isovaleryl-CoA dehydrogenase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300016K07Rik; 6720455E18Rik; AI463340; isovaleryl dehydrogenase; isovaleryl-CoA dehydrogenase, mitochondrial
Homo sapiens (human) : IVD (isovaleryl-CoA dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ivd (isovaleryl-CoA dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ivd (isovaleryl-CoA dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : IVD (isovaleryl-CoA dehydrogenase)
Canis lupus familiaris (dog) : IVD (isovaleryl-CoA dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ivd (isovaleryl-CoA dehydrogenase)
Sus scrofa (pig) : IVD (isovaleryl-CoA dehydrogenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382118,861,959 - 118,882,909 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,687,736 - 118,707,093 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,553,441 - 118,572,798 (+)NCBImm8
Celera2120,013,107 - 120,032,696 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ivd
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735607
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.