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Gene: IL4R (interleukin 4 receptor) Homo sapiens
Symbol: IL4R
Name: interleukin 4 receptor
Description: Predicted to have interleukin-4 receptor activity. Predicted to be involved in positive regulation of cold-induced thermogenesis. Localizes to several cellular components, including centriolar satellite; nucleoplasm; and receptor complex. Implicated in several diseases, including acne; allergic conjunctivitis; human immunodeficiency virus infectious disease; multiple sclerosis (multiple); and renal tuberculosis. Biomarker of asthma; cholangiocarcinoma; osteoarthritis; pancreatic cancer (multiple); and tuberculosis (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD124; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; IL4R nirs variant 1; IL4RA; interleukin 13 receptor; interleukin 4 receptor alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha
Mus musculus (house mouse) : Il4ra (interleukin 4 receptor, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il4r (interleukin 4 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il4r (interleukin 4 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL4R (interleukin 4 receptor)
Canis lupus familiaris (dog) : IL4R (interleukin 4 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il4r (interleukin 4 receptor)
Sus scrofa (pig) : IL4R (interleukin 4 receptor)
Chlorocebus sabaeus (African green monkey) : IL4R (interleukin 4 receptor)
Heterocephalus glaber (naked mole-rat) : Il4r (interleukin 4 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1627,313,668 - 27,364,778 (+)EnsemblGRCh38hg38GRCh38
GRCh381627,313,668 - 27,364,778 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371627,325,161 - 27,376,099 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361627,232,752 - 27,283,600 (+)NCBINCBI36hg18NCBI36
Build 341627,232,751 - 27,274,031NCBI
Celera1626,102,563 - 26,153,416 (+)NCBI
Cytogenetic Map16p12.1NCBI
HuRef1625,413,538 - 25,464,524 (+)NCBIHuRef
CHM1_11628,336,783 - 28,387,655 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL4R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735615
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.