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Gene: QPCT (glutaminyl-peptide cyclotransferase) Homo sapiens
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Symbol: QPCT
Name: glutaminyl-peptide cyclotransferase
Description: Exhibits glutaminyl-peptide cyclotransferase activity and zinc ion binding activity. Involved in peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EC; GCT; glutaminyl cyclase; glutaminyl-peptide cyclotransferase (glutaminyl cyclase); glutaminyl-tRNA cyclotransferase; glutamyl cyclase; QC; sQC
Orthologs:
Mus musculus (house mouse) : Qpct (glutaminyl-peptide cyclotransferase (glutaminyl cyclase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Qpct (glutaminyl-peptide cyclotransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Qpct (glutaminyl-peptide cyclotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : QPCT (glutaminyl-peptide cyclotransferase)
Canis lupus familiaris (dog) : QPCT (glutaminyl-peptide cyclotransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Qpct (glutaminyl-peptide cyclotransferase)
Sus scrofa (pig) : QPCT (glutaminyl-peptide cyclotransferase)
Chlorocebus sabaeus (green monkey) : QPCT (glutaminyl-peptide cyclotransferase)
Heterocephalus glaber (naked mole-rat) : Qpct (glutaminyl-peptide cyclotransferase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl237,342,827 - 37,373,322 (+)Ensembl
GRCh38237,344,630 - 37,373,322 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37237,571,742 - 37,600,465 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,425,257 - 37,453,969 (+)NCBINCBI36hg18NCBI36
Build 34237,483,519 - 37,512,115NCBI
Celera237,412,695 - 37,441,406 (+)NCBI
Cytogenetic Map2p22.2NCBI
HuRef237,311,579 - 37,340,390 (+)NCBIHuRef
CHM1_1237,501,200 - 37,529,906 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on QPCT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735639
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.