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Gene: GATA6 (GATA binding protein 6) Homo sapiens
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Symbol: GATA6
Name: GATA binding protein 6
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; protein kinase binding activity; and transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; negative regulation of transforming growth factor beta production; and regulation of transcription by RNA polymerase II. Localizes to nuclear membrane and nucleoplasm. Implicated in colorectal adenocarcinoma and congenital heart disease (multiple). Biomarker of Barrett's esophagus and pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ASD9; AVSD5; GATA-binding factor 6; GATA-binding protein 6; PACHD; transcription factor GATA-6
Orthologs:
Mus musculus (house mouse) : Gata6 (GATA binding protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gata6 (GATA binding protein 6)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GATA6 (GATA binding protein 6)
Canis lupus familiaris (dog) : GATA6 (GATA binding protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata6 (GATA binding protein 6)
Sus scrofa (pig) : GATA6 (GATA binding protein 6)
Chlorocebus sabaeus (African green monkey) : GATA6 (GATA binding protein 6)
Heterocephalus glaber (naked mole-rat) : Gata6 (GATA binding protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1822,169,392 - 22,202,528 (+)EnsemblGRCh38hg38GRCh38
GRCh381822,169,589 - 22,202,528 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371819,749,404 - 19,782,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361818,003,414 - 18,036,225 (+)NCBINCBI36hg18NCBI36
Build 341818,003,413 - 18,036,225NCBI
Celera1816,555,843 - 16,588,650 (+)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1816,596,234 - 16,629,323 (+)NCBIHuRef
CHM1_11819,676,420 - 19,709,511 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GATA6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735650
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.