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Gene: Pf4 (platelet factor 4) Mus musculus
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Symbol: Pf4
Name: platelet factor 4
Description: Predicted to have CXCR3 chemokine receptor binding activity; chemokine activity; and heparin binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to protozoan. Localizes to collagen-containing extracellular matrix. Is expressed in several structures, including blood vessel; bone marrow; central nervous system; liver; and yolk sac. Orthologous to several human genes including PF4 (platelet factor 4); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Cxcl4; PF-4; Scyb4
Orthologs:
Homo sapiens (human) : PF4 (platelet factor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pf4 (platelet factor 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PF4 (platelet factor 4)
Sus scrofa (pig) : LOC100524373 (platelet factor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl590,772,435 - 90,773,383 (+)EnsemblGRCm38mm10GRCm38
GRCm38590,772,435 - 90,773,383 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37591,201,461 - 91,202,409 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,847,713 - 91,848,583 (+)NCBImm8
Celera588,924,056 - 88,925,004 (+)NCBICelera
Cytogenetic Map5E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pf4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735658
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.