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Gene: NCOA6 (nuclear receptor coactivator 6) Homo sapiens
Symbol: NCOA6
Name: nuclear receptor coactivator 6
Description: Exhibits enzyme binding activity; nuclear receptor transcription coactivator activity; and thyroid hormone receptor binding activity. Involved in several processes, including DNA-templated transcription, initiation; myeloid cell differentiation; and positive regulation of transcription by RNA polymerase II. Localizes to the cytosol and histone methyltransferase complex. Implicated in breast cancer; colon cancer; and lung cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activating signal cointegrator 2; activating signal cointegrator-2; AIB3; amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ANTP; ASC2; cancer-amplified transcriptional coactivator ASC-2; HOX1.1; HOXA7; KIAA0181; NRC; NRC RAP250; nuclear receptor coactivator RAP250; nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor-interacting protein; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; thyroid hormone receptor-binding protein; TRBP
Mus musculus (house mouse) : Ncoa6 (nuclear receptor coactivator 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ncoa6 (nuclear receptor coactivator 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa6 (nuclear receptor coactivator 6)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA6 (nuclear receptor coactivator 6)
Canis lupus familiaris (dog) : NCOA6 (nuclear receptor coactivator 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa6 (nuclear receptor coactivator 6)
Sus scrofa (pig) : NCOA6 (nuclear receptor coactivator 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382034,714,774 - 34,825,651 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372033,302,578 - 33,413,433 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,766,239 - 32,877,094 (-)NCBINCBI36hg18NCBI36
Build 342032,766,238 - 32,877,094NCBI
Celera2030,051,663 - 30,162,529 (-)NCBI
Cytogenetic Map20q11.22NCBI
HuRef2030,081,569 - 30,192,220 (-)NCBIHuRef
CHM1_12033,204,060 - 33,314,842 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NCOA6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735677
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.