Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NCOA6 (nuclear receptor coactivator 6) Homo sapiens
Analyze
Symbol: NCOA6
Name: nuclear receptor coactivator 6
Description: Exhibits enzyme binding activity; nuclear receptor transcription coactivator activity; and thyroid hormone receptor binding activity. Involved in several processes, including DNA-templated transcription, initiation; myeloid cell differentiation; and positive regulation of transcription by RNA polymerase II. Localizes to the cytosol and histone methyltransferase complex. Implicated in breast cancer; colon cancer; and lung cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activating signal cointegrator 2; activating signal cointegrator-2; AIB3; amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ANTP; ASC2; cancer-amplified transcriptional coactivator ASC-2; HOX1.1; HOXA7; KIAA0181; NRC; NRC RAP250; nuclear receptor coactivator RAP250; nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor-interacting protein; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; thyroid hormone receptor-binding protein; TRBP
Orthologs:
Mus musculus (house mouse) : Ncoa6 (nuclear receptor coactivator 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ncoa6 (nuclear receptor coactivator 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa6 (nuclear receptor coactivator 6)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA6 (nuclear receptor coactivator 6)
Canis lupus familiaris (dog) : NCOA6 (nuclear receptor coactivator 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa6 (nuclear receptor coactivator 6)
Sus scrofa (pig) : NCOA6 (nuclear receptor coactivator 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382034,714,774 - 34,825,651 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372033,302,578 - 33,413,433 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,766,239 - 32,877,094 (-)NCBINCBI36hg18NCBI36
Build 342032,766,238 - 32,877,094NCBI
Celera2030,051,663 - 30,162,529 (-)NCBI
Cytogenetic Map20q11.22NCBI
HuRef2030,081,569 - 30,192,220 (-)NCBIHuRef
CHM1_12033,204,060 - 33,314,842 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NCOA6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735677
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.