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Gene: Gria1 (glutamate receptor, ionotropic, AMPA1 (alpha 1)) Mus musculus
Symbol: Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Description: Exhibits neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in several processes, including long-term memory; long-term synaptic depression; and receptor internalization. Localizes to several cellular components, including dendrite membrane; integral component of plasma membrane; and neuron spine. Used to study schizoaffective disorder. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; Reelin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2-tert-butylhydroquinone; arsenite(3-).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900051M01Rik; AI853806; AMPA-selective glutamate receptor 1; Glr-1; Glr1; GluA1; Glur-1; GluR-A; gluR-K1; Glur1; GluRA; glutamate receptor 1; glutamate receptor A; glutamate receptor ionotropic, AMPA 1; HIPA1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1157,011,387 - 57,330,244 (+)EnsemblGRCm38mm10GRCm38
GRCm381157,011,571 - 57,330,244 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371156,825,193 - 57,143,746 (+)NCBIGRCm37mm9NCBIm37
MGSCv361156,855,379 - 57,146,439 (+)NCBImm8
Celera1161,935,002 - 62,079,468 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1134.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gria1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735685
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-05-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.