Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MAP2K5 (mitogen-activated protein kinase kinase 5) Homo sapiens
Symbol: MAP2K5
Name: mitogen-activated protein kinase kinase 5
CRRD ID: 735708
Description: Predicted to have MAP kinase kinase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of cell migration involved in sprouting angiogenesis; and regulation of gene expression. Predicted to localize to cytosol; nucleus; and spindle. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5; MAPKK 5; MAPKK5; MEK 5; MEK5; PRKMK5
Mus musculus (house mouse) : Map2k5 (mitogen-activated protein kinase kinase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Map2k5 (mitogen activated protein kinase kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k5 (mitogen-activated protein kinase kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Canis lupus familiaris (dog) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k5 (mitogen-activated protein kinase kinase 5)
Sus scrofa (pig) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Chlorocebus sabaeus (African green monkey) : MAP2K5 (mitogen-activated protein kinase kinase 5)
Heterocephalus glaber (naked mole-rat) : Map2k5 (mitogen-activated protein kinase kinase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1567,542,703 - 67,807,117 (+)EnsemblGRCh38hg38GRCh38
GRCh381567,542,685 - 67,807,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371567,835,021 - 68,099,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361565,622,075 - 65,886,506 (+)NCBINCBI36hg18NCBI36
Build 341565,719,944 - 65,886,505NCBI
Celera1544,722,555 - 44,987,508 (+)NCBI
Cytogenetic Map15q23NCBI
HuRef1544,669,592 - 44,933,408 (+)NCBIHuRef
CHM1_11567,952,970 - 68,217,538 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MAP2K5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735708
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.