Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ACTC1 (actin alpha cardiac muscle 1) Homo sapiens
Analyze
Symbol: ACTC1
Name: actin alpha cardiac muscle 1
Description: Exhibits ATP binding activity; ATPase activity; and myosin binding activity. Involved in actin-myosin filament sliding and heart contraction. Localizes to the actomyosin, actin portion and sarcomere. Implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACTC; actin alpha cardiac 1; actin, alpha cardiac muscle 1; actin, alpha, cardiac muscle 1; alpha-cardiac actin; ASD5; CMD1R; CMH11; LVNC4
Orthologs:
Mus musculus (house mouse) : Actc1 (actin, alpha, cardiac muscle 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Actc1 (actin, alpha, cardiac muscle 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actc1 (actin alpha cardiac muscle 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTC1 (actin alpha cardiac muscle 1)
Canis lupus familiaris (dog) : ACTC1 (actin alpha cardiac muscle 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actc1 (actin alpha cardiac muscle 1)
Sus scrofa (pig) : ACTC1 (actin alpha cardiac muscle 1)
Chlorocebus sabaeus (African green monkey) : ACTC1 (actin alpha cardiac muscle 1)
Heterocephalus glaber (naked mole-rat) : Actc1 (actin alpha cardiac muscle 1)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   LDLPS4_H   BW284_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1534,790,230 - 34,795,549 (-)Ensembl
GRCh381534,790,230 - 34,795,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371535,080,297 - 35,087,927 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361532,867,589 - 32,875,219 (-)NCBINCBI36hg18NCBI36
Build 341532,869,723 - 32,875,153NCBI
Celera1511,839,644 - 11,847,274 (-)NCBI
Cytogenetic Map15q14ENTREZGENE
HuRef1511,925,790 - 11,933,402 (-)NCBIHuRef
CHM1_11535,198,283 - 35,205,917 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ACTC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735789
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.