Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: STS (steroid sulfatase) Homo sapiens
Analyze
Symbol: STS
Name: steroid sulfatase
Description: This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARSC; ARSC1; arylsulfatase C; ASC; ES; estrone sulfatase; SSDD; steroid sulfatase (microsomal), isozyme S; steryl-sulfatase; steryl-sulfate sulfohydrolase; XLI
Orthologs:
Mus musculus (house mouse) : Sts (steroid sulfatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sts (steroid sulfatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sts (steroid sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : STS (steroid sulfatase)
Canis lupus familiaris (dog) : STS (steroid sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sts (steroid sulfatase)
Sus scrofa (pig) : STS (steroid sulfatase)
more info ...
Related Pseudogenes: STSP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X7,147,252 - 7,354,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X7,065,298 - 7,272,682 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X7,147,472 - 7,282,682 (+)NCBINCBI36hg18NCBI36
Build 34X6,997,232 - 7,132,416NCBI
CeleraX11,363,616 - 11,498,571 (+)NCBI
Cytogenetic MapXp22.31NCBI
HuRefX4,994,733 - 5,130,162 (+)NCBIHuRef
CHM1_1X7,096,353 - 7,303,668 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on STS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735809
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.