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Gene: Adam10 (a disintegrin and metallopeptidase domain 10) Mus musculus
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Symbol: Adam10
Name: a disintegrin and metallopeptidase domain 10
Description: Exhibits peptidase activity, acting on L-amino acid peptides; protein homodimerization activity; and protein kinase binding activity. Involved in several processes, including cochlea development; proteolysis; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Localizes to several cellular components, including the glutamatergic synapse; pore complex; and postsynaptic density. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Is expressed in several structures, including brain; cranial ganglion; foregut-midgut junction; genitourinary system; and sensory organ. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1700031C13Rik; a disintegrin and metalloprotease domain (ADAM) 10; a disintegrin and metalloprotease domain 10; ADAM 10; disintegrin and metalloproteinase domain-containing protein 10; kuz; kuzbanian; kuzbanian protein homolog; MADM; mammalian disintegrin-metalloprotease
Orthologs:
Homo sapiens (human) : ADAM10 (ADAM metallopeptidase domain 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adam10 (ADAM metallopeptidase domain 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam10 (ADAM metallopeptidase domain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM10 (ADAM metallopeptidase domain 10)
Canis lupus familiaris (dog) : ADAM10 (ADAM metallopeptidase domain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam10 (ADAM metallopeptidase domain 10)
Sus scrofa (pig) : ADAM10 (ADAM metallopeptidase domain 10)
Chlorocebus sabaeus (African green monkey) : ADAM10 (ADAM metallopeptidase domain 10)
Heterocephalus glaber (naked mole-rat) : Adam10 (ADAM metallopeptidase domain 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl970,678,997 - 70,780,229 (+)Ensembl
GRCm38970,678,944 - 70,780,229 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37970,526,808 - 70,628,036 (+)NCBIGRCm37mm9NCBIm37
MGSCv36970,478,343 - 70,577,515 (+)NCBImm8
Celera967,896,038 - 67,997,081 (+)NCBICelera
Cytogenetic Map9 DNCBI
cM Map939.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adam10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735848
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.