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Gene: EPO (erythropoietin) Homo sapiens
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Symbol: EPO
Name: erythropoietin
Description: Exhibits cytokine activity and erythropoietin receptor binding activity. Involved in several processes, including negative regulation of ion transport; regulation of signal transduction; and regulation of transcription, DNA-templated. Localizes to the cell surface and extracellular space. Implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Biomarker of amyotrophic lateral sclerosis; anemia; breast cancer; eye disease (multiple); and glucose metabolism disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DBAL; ECYT5; EP; epoetin; MGC138142; MVCD2
Orthologs:
Mus musculus (house mouse) : Epo (erythropoietin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Epo (erythropoietin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epo (erythropoietin)
Pan paniscus (bonobo/pygmy chimpanzee) : EPO (erythropoietin)
Canis lupus familiaris (dog) : EPO (erythropoietin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epo (erythropoietin)
Sus scrofa (pig) : EPO (erythropoietin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,720,468 - 100,723,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,318,423 - 100,321,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,156,359 - 100,159,259 (+)NCBINCBI36hg18NCBI36
Build 34799,963,073 - 99,965,972NCBI
Celera795,048,997 - 95,051,893 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef794,949,230 - 94,952,126 (+)NCBIHuRef
CHM1_17100,248,723 - 100,251,623 (+)NCBICHM1_1
CRA_TCAGchr7v2799,678,028 - 99,680,928 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EPO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735849
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.