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Gene: EPO (erythropoietin) Homo sapiens
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Symbol: EPO
Name: erythropoietin
CRRD ID: 735849
Description: Exhibits cytokine activity and erythropoietin receptor binding activity. Involved in several processes, including negative regulation of ion transport; regulation of signal transduction; and regulation of transcription, DNA-templated. Localizes to cell surface and extracellular space. Implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Biomarker of amyotrophic lateral sclerosis; anemia; breast cancer; eye disease (multiple); and glucose metabolism disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DBAL; ECYT5; EP; epoetin; MGC138142; MVCD2
Orthologs:
Mus musculus (house mouse) : Epo (erythropoietin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Epo (erythropoietin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epo (erythropoietin)
Pan paniscus (bonobo/pygmy chimpanzee) : EPO (erythropoietin)
Canis lupus familiaris (dog) : EPO (erythropoietin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epo (erythropoietin)
Sus scrofa (pig) : EPO (erythropoietin)
Chlorocebus sabaeus (African green monkey) : EPO (erythropoietin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7100,720,468 - 100,723,700 (+)EnsemblGRCh38hg38GRCh38
GRCh387100,720,468 - 100,723,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,318,423 - 100,321,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,156,359 - 100,159,259 (+)NCBINCBI36hg18NCBI36
Build 34799,963,073 - 99,965,972NCBI
Celera795,048,997 - 95,051,893 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef794,949,230 - 94,952,126 (+)NCBIHuRef
CHM1_17100,248,723 - 100,251,623 (+)NCBICHM1_1
CRA_TCAGchr7v2799,678,028 - 99,680,928 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EPO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735849
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.