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Gene: GAPDH (glyceraldehyde-3-phosphate dehydrogenase) Homo sapiens
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Symbol: GAPDH
Name: glyceraldehyde-3-phosphate dehydrogenase
Description: Exhibits aspartic-type endopeptidase inhibitor activity; disordered domain specific binding activity; and identical protein binding activity. Involved in several processes, including defense response to other organism; negative regulation of cellular protein metabolic process; and positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction. Localizes to several cellular components, including the GAIT complex; lipid droplet; and nuclear membrane. Implicated in Alzheimer's disease. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aging-associated gene 9 protein; epididymis secretory sperm binding protein Li 162eP; G3PD; GAPD; glyceraldehyde 3-phosphate dehydrogenase; HEL-S-162eP; MGC88685; OCAS, p38 component; Oct1 coactivator in S phase, 38 Kd component; peptidyl-cysteine S-nitrosylase GAPDH
Orthologs:
Mus musculus (house mouse) : Gapdh (glyceraldehyde-3-phosphate dehydrogenase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gapdh (glyceraldehyde-3-phosphate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gapdh (glyceraldehyde-3-phosphate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : GAPDH (glyceraldehyde-3-phosphate dehydrogenase)
Canis lupus familiaris (dog) : GAPDH (glyceraldehyde-3-phosphate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gapdh (glyceraldehyde-3-phosphate dehydrogenase)
Sus scrofa (pig) : GAPDH (glyceraldehyde-3-phosphate dehydrogenase)
Chlorocebus sabaeus (green monkey) : GAPDH (glyceraldehyde-3-phosphate dehydrogenase)
Heterocephalus glaber (naked mole-rat) : Gapdh (glyceraldehyde-3-phosphate dehydrogenase)
more info ...
Related Pseudogenes: GAPDHP1   GAPDHP14   GAPDHP15   GAPDHP16   GAPDHP17   GAPDHP19   GAPDHP2   GAPDHP20   GAPDHP21   GAPDHP22   GAPDHP23   GAPDHP24   GAPDHP25   GAPDHP26   GAPDHP27   GAPDHP28   GAPDHP29   GAPDHP30   GAPDHP31   GAPDHP32   GAPDHP33   GAPDHP34   GAPDHP35   GAPDHP36   GAPDHP37   GAPDHP38   GAPDHP39   GAPDHP40   GAPDHP41   GAPDHP42   GAPDHP43   GAPDHP45   GAPDHP46   GAPDHP47   GAPDHP48   GAPDHP49   GAPDHP50   GAPDHP51   GAPDHP52   GAPDHP53   GAPDHP54   GAPDHP55   GAPDHP56   GAPDHP57   GAPDHP58   GAPDHP59   GAPDHP60   GAPDHP61   GAPDHP62   GAPDHP63   GAPDHP64   GAPDHP65   GAPDHP66   GAPDHP67   GAPDHP68   GAPDHP69   GAPDHP70   GAPDHP71   GAPDHP72   GAPDHP73   GAPDHP74   GAPDHP75   GAPDHP76  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl126,534,512 - 6,538,374 (+)Ensembl
GRCh38126,534,517 - 6,538,371 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,643,585 - 6,647,537 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,513,918 - 6,517,797 (+)NCBINCBI36hg18NCBI36
Build 34126,513,944 - 6,517,797NCBI
Celera128,260,518 - 8,264,397 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,497,829 - 6,501,781 (+)NCBIHuRef
CHM1_1126,642,578 - 6,646,548 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on GAPDH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735871
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.