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Gene: Reln (reelin) Mus musculus
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Symbol: Reln
Name: reelin
Description: Exhibits very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including nervous system development; positive regulation of cell communication; and postsynaptic membrane organization. Localizes to several cellular components, including the dendrite; extracellular matrix; and extracellular space. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; and familial temporal lobe epilepsy 7. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human RELN (reelin); PARTICIPATES IN Reelin signaling pathway; altered Reelin signaling pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: extracellular matrix serine protease; reeler; rl
Orthologs:
Homo sapiens (human) : RELN (reelin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Reln (reelin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Reln (reelin)
Pan paniscus (bonobo/pygmy chimpanzee) : RELN (reelin)
Canis lupus familiaris (dog) : RELN (reelin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Reln (reelin)
Sus scrofa (pig) : RELN (reelin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38521,884,454 - 22,344,705 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37521,390,272 - 21,850,523 (-)NCBIGRCm37mm9NCBIm37
MGSCv36521,396,293 - 21,856,514 (-)NCBImm8
Celera518,857,999 - 19,307,447 (-)NCBICelera
Cytogenetic Map5 A3NCBI
cM Map59.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Reln
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735881
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.