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Gene: AMACR (alpha-methylacyl-CoA racemase) Homo sapiens
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Symbol: AMACR
Name: alpha-methylacyl-CoA racemase
Description: Exhibits alpha-methylacyl-CoA racemase activity and signaling receptor binding activity. Involved in bile acid metabolic process. Localizes to mitochondrion; peroxisome; and plasma membrane. Implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder cancer. Biomarker of breast carcinoma; prostate carcinoma in situ; and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2-methylacyl-CoA racemase; AMACRD; CBAS4; P504S; RACE; RM
Orthologs:
Mus musculus (house mouse) : Amacr (alpha-methylacyl-CoA racemase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Amacr (alpha-methylacyl-CoA racemase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amacr (alpha-methylacyl-CoA racemase)
Pan paniscus (bonobo/pygmy chimpanzee) : AMACR (alpha-methylacyl-CoA racemase)
Canis lupus familiaris (dog) : AMACR (alpha-methylacyl-CoA racemase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amacr (alpha-methylacyl-CoA racemase)
Sus scrofa (pig) : AMACR (alpha-methylacyl-CoA racemase)
Chlorocebus sabaeus (African green monkey) : AMACR (alpha-methylacyl-CoA racemase)
Heterocephalus glaber (naked mole-rat) : Amacr (alpha-methylacyl-CoA racemase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl533,986,165 - 34,008,104 (-)EnsemblGRCh38hg38GRCh38
GRCh38533,986,165 - 34,008,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37533,987,091 - 34,008,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36534,023,652 - 34,043,963 (-)NCBINCBI36hg18NCBI36
Build 34534,023,658 - 34,043,963NCBI
Celera533,875,521 - 33,896,657 (-)NCBI
Cytogenetic Map5p13.2NCBI
HuRef533,965,051 - 33,986,185 (-)NCBIHuRef
CHM1_1533,988,659 - 34,009,789 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on AMACR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735888
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.