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Gene: Plec (plectin) Mus musculus
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Symbol: Plec
Name: plectin
Description: Predicted to have ankyrin binding activity and protein N-terminus binding activity. Predicted to be involved in several processes, including hemidesmosome assembly; intermediate filament cytoskeleton organization; and response to nutrient. Localizes to the brush border and contractile fiber. Predicted to colocalize with the intermediate filament. Used to study epidermolysis bullosa simplex Ogna type and epidermolysis bullosa simplex with muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Q; epidermolysis bullosa simplex; epidermolysis bullosa simplex Ogna type; and epidermolysis bullosa simplex with muscular dystrophy. Is expressed in retina and skin. Orthologous to human PLEC (plectin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA591047; AU042537; EBS1; PCN; Plec1; plectin 1; plectin-1; plectin-6; PLTN
Orthologs:
Homo sapiens (human) : PLEC (plectin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plec (plectin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plec (plectin)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEC (plectin)
Canis lupus familiaris (dog) : PLEC (plectin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957084 (plectin)
Sus scrofa (pig) : PLEC (plectin)
Chlorocebus sabaeus (African green monkey) : PLEC (plectin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1576,170,974 - 76,232,574 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,170,974 - 76,231,378 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,001,404 - 76,061,808 (-)NCBIGRCm37mm9NCBIm37
MGSCv361575,998,231 - 76,058,633 (-)NCBImm8
Celera1577,670,771 - 77,731,324 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Cell Lines
Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Plec
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735905
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.