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Gene: Cav3 (caveolin 3) Mus musculus
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Symbol: Cav3
Name: caveolin 3
Description: Exhibits alpha-tubulin binding activity; connexin binding activity; and ion channel binding activity. Involved in several processes, including regulation of protein phosphorylation; regulation of signal transduction; and striated muscle cell differentiation. Localizes to the T-tubule and caveola. Predicted to colocalize with several cellular components, including the Z disc; focal adhesion; and intercalated disc. Used to study hypertrophic cardiomyopathy and rippling muscle disease 2. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); isolated elevated serum creatine phosphokinase levels; and muscle tissue disease (multiple). Is expressed in several structures, including alimentary system; diaphragm; head mesenchyme; heart ventricle; and skeletal musculature. Orthologous to human CAV3 (caveolin 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI385751; Cav-3; caveolin-3; M-cav; M-caveolin
Orthologs:
Homo sapiens (human) : CAV3 (caveolin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cav3 (caveolin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav3 (caveolin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV3 (caveolin 3)
Canis lupus familiaris (dog) : CAV3 (caveolin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav3 (caveolin 3)
Sus scrofa (pig) : CAV3 (caveolin 3)
Chlorocebus sabaeus (green monkey) : CAV3 (caveolin 3)
Heterocephalus glaber (naked mole-rat) : Cav3 (caveolin 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6112,459,505 - 112,472,872 (+)Ensembl
GRCm386112,459,505 - 112,472,872 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376112,409,499 - 112,422,866 (+)NCBIGRCm37mm9NCBIm37
MGSCv366112,425,278 - 112,438,649 (+)NCBImm8
Celera6114,297,536 - 114,310,896 (+)NCBICelera
Cytogenetic Map6 E3NCBI
cM Map652.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cav3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735906
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.