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Gene: Cav3 (caveolin 3) Mus musculus
Symbol: Cav3
Name: caveolin 3
Description: Exhibits alpha-tubulin binding activity; connexin binding activity; and ion channel binding activity. Involved in several processes, including regulation of protein phosphorylation; regulation of signal transduction; and striated muscle cell differentiation. Localizes to the T-tubule and caveola. Predicted to colocalize with several cellular components, including the Z disc; focal adhesion; and intercalated disc. Used to study hypertrophic cardiomyopathy and rippling muscle disease 2. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); isolated elevated serum creatine phosphokinase levels; and muscle tissue disease (multiple). Is expressed in several structures, including alimentary system; diaphragm; head mesenchyme; heart ventricle; and skeletal musculature. Orthologous to human CAV3 (caveolin 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI385751; Cav-3; caveolin-3; M-cav; M-caveolin
Homo sapiens (human) : CAV3 (caveolin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cav3 (caveolin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav3 (caveolin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV3 (caveolin 3)
Canis lupus familiaris (dog) : CAV3 (caveolin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav3 (caveolin 3)
Sus scrofa (pig) : CAV3 (caveolin 3)
Chlorocebus sabaeus (green monkey) : CAV3 (caveolin 3)
Heterocephalus glaber (naked mole-rat) : Cav3 (caveolin 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6112,459,505 - 112,472,872 (+)Ensembl
GRCm386112,459,505 - 112,472,872 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376112,409,499 - 112,422,866 (+)NCBIGRCm37mm9NCBIm37
MGSCv366112,425,278 - 112,438,649 (+)NCBImm8
Celera6114,297,536 - 114,310,896 (+)NCBICelera
Cytogenetic Map6 E3NCBI
cM Map652.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cav3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735906
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.