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Gene: Chrna2 (cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)) Mus musculus
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Symbol: Chrna2
Name: cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
Description: Predicted to contribute to acetylcholine binding activity and acetylcholine receptor activity. Predicted to be involved in several processes, including chemical synaptic transmission; regulation of membrane potential; and response to nicotine. Localizes to cell periphery. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 4. Orthologous to human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Acra-2; Acra2; BC011490; MGC18795; neuronal acetylcholine receptor subunit alpha-2
Orthologs:
Homo sapiens (human) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Canis lupus familiaris (dog) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
Sus scrofa (pig) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Heterocephalus glaber (naked mole-rat) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1466,135,039 - 66,152,948 (+)EnsemblGRCm38mm10GRCm38
GRCm381466,133,236 - 66,152,948 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371466,759,797 - 66,771,785 (+)NCBIGRCm37mm9NCBIm37
MGSCv361465,095,070 - 65,107,058 (+)NCBImm8
Celera1463,889,359 - 63,901,395 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Chrna2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735908
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.