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Gene: PLA2G1B (phospholipase A2 group IB) Homo sapiens
Symbol: PLA2G1B
Name: phospholipase A2 group IB
Description: Exhibits calcium ion binding activity; calcium-dependent phospholipase A2 activity; and signaling receptor binding activity. Involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to other organism; and positive regulation of fibroblast proliferation. Localizes to the cell surface and extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: group IB phospholipase A2; MGC119834; MGC119835; phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2; phospholipase a2, group ib; phospholipase A2, group IB (pancreas); PLA2; PLA2A; PPLA2
Mus musculus (house mouse) : Pla2g1b (phospholipase A2, group IB, pancreas)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pla2g1b (phospholipase A2 group IB)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g1b (phospholipase A2 group IB)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G1B (phospholipase A2 group IB)
Canis lupus familiaris (dog) : PLA2G1B (phospholipase A2 group IB)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g1b (phospholipase A2 group IB)
Sus scrofa (pig) : PLA2G1B (phospholipase A2 group IB)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12120,322,115 - 120,327,779 (-)Ensembl
GRCh3812120,322,115 - 120,327,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712120,759,914 - 120,765,592 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,244,297 - 119,249,975 (-)NCBINCBI36hg18NCBI36
Build 3412119,222,634 - 119,228,312NCBI
Celera12120,393,029 - 120,398,697 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12117,768,236 - 117,773,905 (-)NCBIHuRef
CHM1_112120,727,838 - 120,733,516 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PLA2G1B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735909
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.