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Gene: MMP16 (matrix metallopeptidase 16) Homo sapiens
Symbol: MMP16
Name: matrix metallopeptidase 16
Description: Exhibits metalloaminopeptidase activity; metalloendopeptidase activity; and zinc ion binding activity. Involved in protein processing. Localizes to the integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C8orf57; chromosome 8 open reading frame 57; DKFZp761D112; matrix metallopeptidase 16 (membrane-inserted); matrix metalloproteinase 16; matrix metalloproteinase-16; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase; MMP-16; MMP-X2; MT-MMP 3; MT-MMP2; MT-MMP3; MT3-MMP; MT3MMP; MTMMP3; Putative transmembrane protein C8orf57
Mus musculus (house mouse) : Mmp16 (matrix metallopeptidase 16)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mmp16 (matrix metallopeptidase 16)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp16 (matrix metallopeptidase 16)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP16 (matrix metallopeptidase 16)
Canis lupus familiaris (dog) : MMP16 (matrix metallopeptidase 16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp16 (matrix metallopeptidase 16)
Sus scrofa (pig) : MMP16 (matrix metallopeptidase 16)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38888,032,009 - 88,327,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37889,049,460 - 89,339,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36889,118,576 - 89,408,833 (-)NCBINCBI36hg18NCBI36
Build 34889,150,576 - 89,408,664NCBI
Celera885,244,102 - 85,534,339 (-)NCBI
Cytogenetic Map8q21.3NCBI
HuRef884,259,378 - 84,549,728 (-)NCBIHuRef
CHM1_1889,091,126 - 89,381,311 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MMP16
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735917
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.