Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: IL5RA (interleukin 5 receptor subunit alpha) Homo sapiens
Symbol: IL5RA
Name: interleukin 5 receptor subunit alpha
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in MAPK cascade; cytokine-mediated signaling pathway; and positive regulation of leukocyte proliferation. Predicted to localize to the external side of plasma membrane and receptor complex. Implicated in asthma. Biomarker of asthma; chronic obstructive pulmonary disease; mastocytosis; and respiratory syncytial virus infectious disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; IL5R; interleukin 5 receptor type 3; interleukin 5 receptor, alpha; interleukin-5 receptor alpha chain; interleukin-5 receptor alpha subunit; interleukin-5 receptor subunit alpha; MGC26560
Mus musculus (house mouse) : Il5ra (interleukin 5 receptor, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il5ra (interleukin 5 receptor subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il5ra (interleukin 5 receptor subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : IL5RA (interleukin 5 receptor subunit alpha)
Canis lupus familiaris (dog) : IL5RA (interleukin 5 receptor subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il5ra (interleukin 5 receptor subunit alpha)
Sus scrofa (pig) : IL5RA (interleukin 5 receptor subunit alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3833,066,324 - 3,110,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3733,108,008 - 3,152,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3633,086,421 - 3,127,031 (-)NCBINCBI36hg18NCBI36
Build 3433,106,856 - 3,127,031NCBI
Celera33,050,635 - 3,091,288 (-)NCBI
Cytogenetic Map3p26.2NCBI
HuRef33,042,189 - 3,086,251 (-)NCBIHuRef
CHM1_133,057,999 - 3,102,013 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL5RA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735921
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.