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Gene: IL5RA (interleukin 5 receptor subunit alpha) Homo sapiens
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Symbol: IL5RA
Name: interleukin 5 receptor subunit alpha
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in MAPK cascade; cytokine-mediated signaling pathway; and positive regulation of leukocyte proliferation. Predicted to localize to the external side of plasma membrane and receptor complex. Implicated in asthma. Biomarker of asthma; chronic obstructive pulmonary disease; mastocytosis; and respiratory syncytial virus infectious disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; IL5R; interleukin 5 receptor type 3; interleukin 5 receptor, alpha; interleukin-5 receptor alpha chain; interleukin-5 receptor alpha subunit; interleukin-5 receptor subunit alpha; MGC26560
Orthologs:
Mus musculus (house mouse) : Il5ra (interleukin 5 receptor, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il5ra (interleukin 5 receptor subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il5ra (interleukin 5 receptor subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : IL5RA (interleukin 5 receptor subunit alpha)
Canis lupus familiaris (dog) : IL5RA (interleukin 5 receptor subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il5ra (interleukin 5 receptor subunit alpha)
Sus scrofa (pig) : IL5RA (interleukin 5 receptor subunit alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3833,066,324 - 3,110,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3733,108,008 - 3,152,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3633,086,421 - 3,127,031 (-)NCBINCBI36hg18NCBI36
Build 3433,106,856 - 3,127,031NCBI
Celera33,050,635 - 3,091,288 (-)NCBI
Cytogenetic Map3p26.2NCBI
HuRef33,042,189 - 3,086,251 (-)NCBIHuRef
CHM1_133,057,999 - 3,102,013 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL5RA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735921
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.