Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Plcg1 (phospholipase C, gamma 1) Mus musculus
Analyze
Symbol: Plcg1
Name: phospholipase C, gamma 1
Description: Exhibits glutamate receptor binding activity; phosphatidylinositol phospholipase C activity; and receptor tyrosine kinase binding activity. Involved in T cell receptor signaling pathway; in utero embryonic development; and modulation of chemical synaptic transmission. Localizes to the Schaffer collateral - CA1 synapse; cell-cell junction; and glutamatergic synapse. Predicted to colocalize with the neuron projection. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and nervous system. Orthologous to human PLCG1 (phospholipase C gamma 1); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; phosphoinositide phospholipase C-gamma-1; phospholipase C-gamma-1; Plc-1; PLC-gamma-1; Plc-gamma1; Plcg-1
Orthologs:
Homo sapiens (human) : PLCG1 (phospholipase C gamma 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcg1 (phospholipase C, gamma 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcg1 (phospholipase C gamma 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCG1 (phospholipase C gamma 1)
Canis lupus familiaris (dog) : PLCG1 (phospholipase C gamma 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcg1 (phospholipase C gamma 1)
Sus scrofa (pig) : PLCG1 (phospholipase C gamma 1)
Chlorocebus sabaeus (African green monkey) : PLCG1 (phospholipase C gamma 1)
Heterocephalus glaber (naked mole-rat) : Plcg1 (phospholipase C gamma 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl2160,731,300 - 160,775,760 (+)Ensembl
GRCm382160,731,310 - 160,775,760 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372160,557,046 - 160,601,496 (+)NCBIGRCm37mm9NCBIm37
MGSCv362160,422,751 - 160,467,201 (+)NCBImm8
Celera2166,663,373 - 166,707,819 (+)NCBICelera
Cytogenetic Map2 H2NCBI
cM Map280.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Plcg1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735937
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.