Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: IL2RA (interleukin 2 receptor subunit alpha) Homo sapiens
Symbol: IL2RA
Name: interleukin 2 receptor subunit alpha
CRRD ID: 735947
Description: Contributes to interleukin-2 receptor activity. Involved in regulation of T cell tolerance induction. Predicted to localize to interleukin-2 receptor complex. Implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Biomarker of COVID-19; Hantavirus hemorrhagic fever with renal syndrome; and idiopathic pulmonary fibrosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD25; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; IL2R; IMD41; insulin-dependent diabetes mellitus 10; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
Mus musculus (house mouse) : Il2ra (interleukin 2 receptor, alpha chain)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il2ra (interleukin 2 receptor subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il2ra (interleukin 2 receptor subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RA (interleukin 2 receptor subunit alpha)
Canis lupus familiaris (dog) : IL2RA (interleukin 2 receptor subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2ra (interleukin 2 receptor subunit alpha)
Sus scrofa (pig) : IL2RA (interleukin 2 receptor subunit alpha)
Chlorocebus sabaeus (African green monkey) : IL2RA (interleukin 2 receptor subunit alpha)
Heterocephalus glaber (naked mole-rat) : Il2ra (interleukin 2 receptor subunit alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for COVID-19 prognosis.
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl106,010,689 - 6,062,370 (-)EnsemblGRCh38hg38GRCh38
GRCh38106,010,689 - 6,062,367 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37106,052,657 - 6,104,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36106,093,512 - 6,144,278 (-)NCBINCBI36hg18NCBI36
Build 34106,093,511 - 6,144,278NCBI
Celera105,982,579 - 6,033,743 (-)NCBI
Cytogenetic Map10p15.1NCBI
HuRef105,979,490 - 6,030,662 (-)NCBIHuRef
CHM1_1106,052,649 - 6,103,793 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL2RA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735947
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.