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Gene: MUC2 (mucin 2, oligomeric mucus/gel-forming) Homo sapiens
Symbol: MUC2
Name: mucin 2, oligomeric mucus/gel-forming
Description: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: intestinal mucin-2; MLP; MUC-2; mucin 2, intestinal/tracheal; mucin-2; mucin-like protein; SMUC
Mus musculus (house mouse) : Muc2 (mucin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Muc2 (mucin 2, oligomeric mucus/gel-forming)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Canis lupus familiaris (dog) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc2 (mucin 2, oligomeric mucus/gel-forming)
Sus scrofa (pig) : MUC2 (mucin 2, oligomeric mucus/gel-forming)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: partial on reference assembly
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38111,074,875 - 1,110,508 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37111,074,875 - 1,104,417 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,064,902 - 1,094,419 (+)NCBINCBI36hg18NCBI36
Build 34111,064,874 - 1,094,416NCBI
Cytogenetic Map11p15.5NCBI
HuRef11897,783 - 932,205 (+)NCBIHuRef
CHM1_1111,073,796 - 1,103,732 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MUC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735987
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.