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Gene: KLRK1 (killer cell lectin like receptor K1) Homo sapiens
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Symbol: KLRK1
Name: killer cell lectin like receptor K1
Description: Exhibits signaling receptor activity. Involved in several processes, including negative regulation of GTPase activity; negative regulation of natural killer cell chemotaxis; and positive regulation of natural killer cell mediated cytotoxicity. Localizes to cell surface and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD314; D12S2489E; FLJ17759; FLJ75772; killer cell lectin-like receptor subfamily K, member 1; KLR; NK cell receptor D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKG2D; nkr-p2, ortholog of human nkg2d
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1210,372,353 - 10,391,874 (-)EnsemblGRCh38hg38GRCh38
GRCh381210,372,353 - 10,390,041 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371210,524,952 - 10,542,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,416,219 - 10,451,632 (-)NCBINCBI36hg18NCBI36
Build 341210,416,219 - 10,451,632NCBI
Celera1215,686,800 - 15,704,498 (-)NCBI
Cytogenetic Map12p13.2NCBI
HuRef1210,267,379 - 10,285,074 (-)NCBIHuRef
CHM1_11210,494,385 - 10,512,080 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

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Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KLRK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 735993
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.