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Gene: Col18a1 (collagen, type XVIII, alpha 1) Mus musculus
Symbol: Col18a1
Name: collagen, type XVIII, alpha 1
Description: Predicted to have extracellular matrix structural constituent and identical protein binding activity. Involved in several processes, including angiogenesis; endothelial cell morphogenesis; and positive regulation of endothelial cell apoptotic process. Localizes to the basement membrane. Used to study pigment dispersion syndrome. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human COL18A1 (collagen type XVIII alpha 1 chain); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1(XVIII) collagen; collagen alpha-1(XVIII) chain; endostatin; procollagen, type XVIII, alpha 1
Homo sapiens (human) : COL18A1 (collagen type XVIII alpha 1 chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Col18a1 (collagen type XVIII alpha 1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col18a1 (collagen type XVIII alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL18A1 (collagen type XVIII alpha 1 chain)
Canis lupus familiaris (dog) : COL18A1 (collagen type XVIII alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col18a1 (collagen type XVIII alpha 1 chain)
Sus scrofa (pig) : COL18A1 (collagen type XVIII alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL18A1 (collagen type XVIII alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col18a1 (collagen type XVIII alpha 1 chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1077,052,178 - 77,166,548 (-)Ensembl
GRCm381077,052,178 - 77,166,530 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371076,514,924 - 76,629,275 (-)NCBIGRCm37mm9NCBIm37
MGSCv361076,495,895 - 76,610,217 (-)NCBImm8
Celera1078,096,179 - 78,210,613 (-)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Col18a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736033
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.