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Gene: GSTM1 (glutathione S-transferase mu 1) Homo sapiens
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Symbol: GSTM1
Name: glutathione S-transferase mu 1
CRRD ID: 736060
Description: Exhibits several functions, including glutathione binding activity; glutathione transferase activity; and protein homodimerization activity. Involved in several processes, including cellular detoxification of nitrogen compound; glutathione derivative biosynthetic process; and unsaturated fatty acid metabolic process. Localizes to cytosol and intercellular bridge. Implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Biomarker of carcinoma (multiple); chronic obstructive pulmonary disease; gallbladder cancer; and macular degeneration.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione s-transferase, mu 1; GST class-mu 1; GST HB subunit 4; GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; HB subunit 4; MGC26563; MU; MU-1; S-(hydroxyalkyl)glutathione lyase
Orthologs:
Mus musculus (house mouse) : Gstm1 (glutathione S-transferase, mu 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gstm1 (glutathione S-transferase mu 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GSTM1 (glutathione S-transferase mu 1)
Chlorocebus sabaeus (African green monkey) : GSTM1 (glutathione S-transferase mu 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1109,687,814 - 109,709,039 (+)EnsemblGRCh38hg38GRCh38
GRCh381109,687,817 - 109,693,745 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371110,230,418 - 110,240,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,031,965 - 110,037,890 (+)NCBINCBI36hg18NCBI36
Build 341109,942,483 - 109,948,409NCBI
Cytogenetic Map1p13.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GSTM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736060
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-11-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.