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Gene: MVD (mevalonate diphosphate decarboxylase) Homo sapiens
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Symbol: MVD
Name: mevalonate diphosphate decarboxylase
Description: Exhibits Hsp70 protein binding activity; diphosphomevalonate decarboxylase activity; and protein homodimerization activity. Involved in isoprenoid biosynthetic process and positive regulation of cell population proliferation. Localizes to cytosol. Implicated in porokeratosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: diphosphomevalonate decarboxylase; FP17780; MDDase; mevalonate (diphospho) decarboxylase; mevalonate pyrophosphate decarboxylase; MPD; POROK7
Orthologs:
Mus musculus (house mouse) : Mvd (mevalonate (diphospho) decarboxylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mvd (mevalonate diphosphate decarboxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mvd (mevalonate diphosphate decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MVD (mevalonate diphosphate decarboxylase)
Canis lupus familiaris (dog) : MVD (mevalonate diphosphate decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mvd (mevalonate diphosphate decarboxylase)
Sus scrofa (pig) : MVD (mevalonate diphosphate decarboxylase)
Chlorocebus sabaeus (African green monkey) : MVD (mevalonate diphosphate decarboxylase)
Heterocephalus glaber (naked mole-rat) : Mvd (mevalonate diphosphate decarboxylase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1688,651,935 - 88,663,161 (-)EnsemblGRCh38hg38GRCh38
GRCh381688,651,935 - 88,663,153 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371688,718,343 - 88,729,495 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,245,849 - 87,256,996 (-)NCBINCBI36hg18NCBI36
Build 341687,245,848 - 87,256,996NCBI
Celera1673,788,020 - 73,799,160 (-)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1674,412,379 - 74,423,531 (-)NCBIHuRef
CHM1_11690,129,698 - 90,140,909 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MVD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736074
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.