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Gene: Eif5 (eukaryotic translation initiation factor 5) Mus musculus
Symbol: Eif5
Name: eukaryotic translation initiation factor 5
Description: Predicted to have GDP-dissociation inhibitor activity; eukaryotic initiation factor eIF2 binding activity; and translation initiation factor activity. Predicted to be involved in activation of GTPase activity; cytoplasmic translational initiation; and regulation of translational initiation. Predicted to localize to the cytosol and plasma membrane. Is expressed in several structures, including central nervous system; dorsal root ganglion; ear; genitourinary system; and retina nuclear layer. Orthologous to human EIF5 (eukaryotic translation initiation factor 5); PARTICIPATES IN translation initiation pathway; INTERACTS WITH (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810011H21Rik; D12Ertd549e; eIF-5; MGC36374; MGC36509
Homo sapiens (human) : EIF5 (eukaryotic translation initiation factor 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Eif5 (eukaryotic translation initiation factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eif5 (eukaryotic translation initiation factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : EIF5 (eukaryotic translation initiation factor 5)
Canis lupus familiaris (dog) : EIF5 (eukaryotic translation initiation factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eif5 (eukaryotic translation initiation factor 5)
Sus scrofa (pig) : EIF5 (eukaryotic translation initiation factor 5)
Chlorocebus sabaeus (green monkey) : EIF5 (eukaryotic translation initiation factor 5)
Heterocephalus glaber (naked mole-rat) : Eif5 (eukaryotic translation initiation factor 5)
more info ...
Related Pseudogenes: Gm11833   Gm18867   Gm18899   Gm18909   Gm5322   Gm5969  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12111,538,016 - 111,546,752 (+)Ensembl
GRCm3812111,538,101 - 111,546,753 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712112,776,312 - 112,784,964 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612111,987,328 - 111,994,247 (+)NCBImm8
Celera12112,732,164 - 112,740,796 (+)NCBICelera
Cytogenetic Map12 F1NCBI
cM Map1261.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Eif5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736123
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.