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Gene: Fbln5 (fibulin 5) Mus musculus
Symbol: Fbln5
Name: fibulin 5
Description: Exhibits integrin binding activity. Involved in elastic fiber assembly; protein localization to cell surface; and regulation of removal of superoxide radicals. Localizes to the extracellular space. Colocalizes with the collagen-containing extracellular matrix and elastic fiber. Used to study cutis laxa. Human ortholog(s) of this gene implicated in age related macular degeneration; autosomal dominant cutis laxa 2; autosomal recessive cutis laxa type IA; and cutis laxa. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and skeleton. Orthologous to human FBLN5 (fibulin 5); INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A55; DANCE; developmental arteries and neural crest EGF-like protein; EVEC; FIBL-5; fibulin-5
Homo sapiens (human) : FBLN5 (fibulin 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbln5 (fibulin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbln5 (fibulin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBLN5 (fibulin 5)
Canis lupus familiaris (dog) : FBLN5 (fibulin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbln5 (fibulin 5)
Sus scrofa (pig) : FBLN5 (fibulin 5)
Chlorocebus sabaeus (African green monkey) : FBLN5 (fibulin 5)
Heterocephalus glaber (naked mole-rat) : Fbln5 (fibulin 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12101,746,565 - 101,819,055 (-)Ensembl
GRCm3812101,746,565 - 101,819,119 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712102,984,775 - 103,057,265 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612102,147,615 - 102,228,101 (-)NCBImm8
Celera12102,955,562 - 103,028,742 (-)NCBICelera
Cytogenetic Map12 ENCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbln5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736146
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.