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Gene: ITGA8 (integrin subunit alpha 8) Homo sapiens
Symbol: ITGA8
Name: integrin subunit alpha 8
CRRD ID: 736147
Description: Predicted to have metal ion binding activity. Involved in several processes, including cell-matrix adhesion; mesodermal cell differentiation; and substrate adhesion-dependent cell spreading. Localizes to cell surface and endoplasmic reticulum. Implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Biomarker of autosomal dominant polycystic kidney disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: integrin alpha 8; integrin alpha-8; integrin, alpha 8
Mus musculus (house mouse) : Itga8 (integrin alpha 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itga8 (integrin subunit alpha 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga8 (integrin subunit alpha 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA8 (integrin subunit alpha 8)
Canis lupus familiaris (dog) : ITGA8 (integrin subunit alpha 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga8 (integrin subunit alpha 8)
Sus scrofa (pig) : ITGA8 (integrin subunit alpha 8)
Chlorocebus sabaeus (African green monkey) : ITGA8 (integrin subunit alpha 8)
Heterocephalus glaber (naked mole-rat) : Itga8 (integrin subunit alpha 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1015,513,954 - 15,719,922 (-)EnsemblGRCh38hg38GRCh38
GRCh381015,513,954 - 15,720,329 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371015,557,711 - 15,762,328 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361015,599,094 - 15,801,776 (-)NCBINCBI36hg18NCBI36
Build 341015,599,093 - 15,801,776NCBI
Celera1015,492,319 - 15,695,021 (-)NCBI
Cytogenetic Map10p13NCBI
HuRef1015,471,650 - 15,674,184 (-)NCBIHuRef
CHM1_11015,556,070 - 15,762,384 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITGA8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736147
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.