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Gene: GBP2 (guanylate binding protein 2) Homo sapiens
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Symbol: GBP2
Name: guanylate binding protein 2
Description: Exhibits protein homodimerization activity. Involved in cellular response to cytokine stimulus and protein localization to nucleus. Localizes to several cellular components, including the Golgi apparatus; actin cytoskeleton; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp451C2311; GBP-2; GTP-binding protein 2; guanine nucleotide-binding protein 2; guanylate binding protein 2, interferon-inducible; guanylate-binding protein 2; huGBP-2; interferon-induced guanylate-binding protein 2
Orthologs:
Mus musculus (house mouse) : Gbp2 (guanylate binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gbp2 (guanylate binding protein 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GBP2 (guanylate binding protein 2)
Sus scrofa (pig) : GBP2 (guanylate binding protein 2, interferon-inducible)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl189,106,132 - 89,150,456 (-)Ensembl
GRCh38189,106,132 - 89,126,114 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37189,571,815 - 89,591,842 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,345,898 - 89,364,387 (-)NCBINCBI36hg18NCBI36
Build 34189,285,330 - 89,303,820NCBI
Celera187,819,109 - 87,837,605 (-)NCBI
Cytogenetic Map1p22.2NCBI
HuRef187,689,164 - 87,709,193 (-)NCBIHuRef
CHM1_1189,686,861 - 89,706,895 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GBP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736152
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.