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Gene: ABCA1 (ATP binding cassette subfamily A member 1) Homo sapiens
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Symbol: ABCA1
Name: ATP binding cassette subfamily A member 1
Description: Exhibits several functions, including anion binding activity; enzyme binding activity; and lipid transporter activity. Involved in several processes, including interleukin-1 beta secretion; lipid homeostasis; and lipid transport. Localizes to several cellular components, including the cytoplasmic vesicle; membrane raft; and perinuclear region of cytoplasm. Implicated in Alzheimer's disease; coronary artery disease; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABC-1; ABC1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, sub-family A (ABC1), member 1; CERP; cholesterol efflux regulatory protein; FLJ14958; HDLCQTL13; HDLDT1; HPALP1; membrane-bound; MGC164864; MGC165011; phospholipid-transporting ATPase ABCA1; TGD
Orthologs:
Mus musculus (house mouse) : Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abca1 (ATP binding cassette subfamily A member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abca1 (ATP binding cassette subfamily A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA1 (ATP binding cassette subfamily A member 1)
Canis lupus familiaris (dog) : ABCA1 (ATP binding cassette subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abca1 (ATP binding cassette subfamily A member 1)
Sus scrofa (pig) : ABCA1 (ATP binding cassette subfamily A member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389104,781,006 - 104,928,232 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379107,543,283 - 107,690,527 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369106,583,104 - 106,730,257 (-)NCBINCBI36hg18NCBI36
Build 349104,622,837 - 104,769,991NCBI
Celera978,048,593 - 78,195,737 (-)NCBI
Cytogenetic Map9q31.1NCBI
HuRef977,145,450 - 77,292,489 (-)NCBIHuRef
CHM1_19107,690,161 - 107,837,338 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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