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Gene: SYK (spleen associated tyrosine kinase) Homo sapiens
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Symbol: SYK
Name: spleen associated tyrosine kinase
Description: Exhibits phosphotyrosine residue binding activity; protein kinase activity; and signaling receptor binding activity. Involved in several processes, including neutrophil chemotaxis; positive regulation of cellular metabolic process; and positive regulation of monocyte chemotactic protein-1 production. Localizes to the T cell receptor complex; cytoplasm; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp313N1010; FLJ25043; FLJ37489; p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK
Orthologs:
Mus musculus (house mouse) : Syk (spleen tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Syk (spleen associated tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syk (spleen associated tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : SYK (spleen associated tyrosine kinase)
Canis lupus familiaris (dog) : SYK (spleen associated tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syk (spleen associated tyrosine kinase)
Sus scrofa (pig) : SYK (spleen associated tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38990,801,600 - 90,898,549 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37993,564,012 - 93,660,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36992,603,891 - 92,698,305 (+)NCBINCBI36hg18NCBI36
Build 34990,643,624 - 90,738,036NCBI
Celera963,998,674 - 64,095,487 (+)NCBI
Cytogenetic Map9q22.2NCBI
HuRef963,244,666 - 63,341,118 (+)NCBIHuRef
CHM1_1993,710,434 - 93,807,287 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SYK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736160
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.