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Gene: GJA5 (gap junction protein alpha 5) Homo sapiens
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Symbol: GJA5
Name: gap junction protein alpha 5
Description: Exhibits gap junction channel activity. Involved in several processes, including circulatory system development; gap junction assembly; and regulation of heart contraction. Localizes to the connexin complex; integral component of plasma membrane; and intercalated disc. Implicated in atrial fibrillation; familial atrial fibrillation; and tetralogy of Fallot. Biomarker of atrial fibrillation.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB11; connexin 40; connexin-40; CX40; gap junction alpha-5 protein; gap junction membrane channel protein alpha 5; gap junction protein alpha 5 40kDa; MGC11185
Orthologs:
Mus musculus (house mouse) : Gja5 (gap junction protein, alpha 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gja5 (gap junction protein, alpha 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gja5 (gap junction protein alpha 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GJA5 (gap junction protein alpha 5)
Canis lupus familiaris (dog) : GJA5 (gap junction protein alpha 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gja5 (gap junction protein alpha 5)
Sus scrofa (pig) : GJA5 (gap junction protein alpha 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,756,199 - 147,781,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371147,228,332 - 147,253,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361145,694,956 - 145,712,108 (-)NCBINCBI36hg18NCBI36
Build 341144,453,708 - 144,457,501NCBI
Celera1121,738,476 - 121,755,641 (+)NCBI
Cytogenetic Map1q21.2NCBI
HuRef1120,641,850 - 120,658,997 (-)NCBIHuRef
CHM1_11149,124,325 - 149,141,488 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GJA5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 736164
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.